Searchable abstracts of presentations at key conferences in endocrinology

ea0020p43 | Adrenal | ECE2009

Iatrogenic Cushing’s syndrome induced by topical corticoid application in child and adult

Branisteanu Dumitru , Turliuc Serban , Veliaj Blenda , Mogos Simona , Zbranca Eusebie , Repede Ionut , Aancute Adrian , Mogos Voichita

Topical application of corticosteroids is frequently used in the therapy of dermatological diseases due to their anti-inflammatory and immunosuppressive effects. On the other hand, when reaching pharmacological levels, exogenous corticoids frequently lead to complete Cushing syndrome, including skin modifications, irrespective of the route of administration. We describe four cases of iatrogenic Cushing’s syndrome triggered by topical application of corticoids. The first t...

ea0049ep213 | Bone & Osteoporosis | ECE2017

Primary hyperparathyroidism: hormonal profile and risk of complications

Gatu Alina-Andreea , Velicescu Cristian , Preda Cristina , Mogos Voichita , Vulpoi Carmen , Mogos Simona , Zaharia Valentin , Aancute Adrian , Branisteanu Dumitru

Background: Vitamin D deficiency is frequently associated with primary hyperparathyroidism, but the impact of this association on disease evolution and complications is ill defined. Aims: to assess the role of vitamin D status on the metabolic profile and spectrum of complications at patients with primary hyperparathyroidism.Materials and methods: Transversal study involving 42 patients with primary hyperparathyroidism submitted to parathyroidectomy. We ...

ea0049ep260 | Calcium & Vitamin D metabolism | ECE2017

How to differentiate primary hyperparathyroidism with D hypovitaminosis from secondary hyperparathyroidism due to D hypovitaminosis?

Gatu Alina-Andreea , Velicescu Cristian , Preda Cristina , Vulpoi Carmen , Mogos Simona , Mogos Voichita , Zaharia Valentin , Aancute Adrian , Branisteanu Dumitru

Background: D hypovitaminosis and primary hyperparathyroidism frequently coexist. Secondary hyperparathyroidism reactive to D hypovitaminosis is difficult to be differentiated from primary hyperparthyroidism.Aims: To differentiate patients with D hypovitaminosis and secondary hyperparathyroidism.Materials and methods: Prospective study involving 71 patients admitted in our department for 1 year with the initial diagnosis of primary...

ea0063gp116 | Calcium and Bone 2 | ECE2019

FGF-23 beyond the kidney: a new bone mass regulator in the general population

Bilha Stefana Catalina , Ungureanu Maria-Christina , Gatu Alina Andreea , Matei Anca , Florescu Alexandru , Aancute Adrian , Zaharia Valentin , Preda Cristina , Covic Adrian , Branisteanu Dumitru

Aim: Fibroblast growth factor-23 (FGF-23) has been proposed as a predictor of bone abnormalities in chronic kidney disease patients (CKD), with recent data showing that it may also predict bone mass in the general population. We aimed at investigating the relationship between FGF-23 and bone mass parameters in apparently healthy individuals, according to sex, menopausal and nutritional status.Materials and methods: Bone mass (bone mineral density-BMD, bo...

ea0049gp34 | Bone & Calcium Homeostasis 1 | ECE2017

Fat mass distribution and resistin are independent predictors of bone mass in postmenopausal, but not premenopausal women.

Bilha Stefana Catalina , Ungureanu Maria-Christina , Cianga Petru , Buzduga Catalin , Aancute Adrian , Zaharia Valentin , Constantinescu Daniela , Anisie Ecaterina , Covic Adrian , Branisteanu Dumitru

Introduction: Body weight and lean mass (LM) are classic bone mass determinants. However, the association between total fat mass (FM), regional FM and bone remains controversial, especially as fat is a source of adipocytokines, with both positive and negative bone consequences.Materials and methods: Anthropometric, bone mass (assessed by Dual X-Ray Absorptiometry; DXA) and body composition parameters (assessed by DXA) and also serum adipocytokine (leptin...

ea0056p185 | Bone ' Osteoporosis | ECE2018

The main bone mass predictors in healthy young and middle-aged men: lean mass and estradiol

Bilha Stefana Catalina , Ungureanu Maria-Christina , Cianga Petru , Buzduga Catalin , Gatu Alina , Aancute Adrian , Zaharia Valentin , Constantinescu Daniela , Covic Adrian , Branisteanu Dumitru

Introduction: Despite the high burden of osteoporotic fractures, bone evaluation in men is not without flaws, being frequently undervalued. We aimed at investigating the role of body composition, adipokines and classic bone determinants (sex hormones) as predictive factors for bone mass parameters in healthy young and middle-aged men.Materials and methods: Anthropometric, bone mineral density (BMD) (assessed by Dual X-Ray Absorptiometry;DXA) and body com...